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==History== The separation of infected people in order to prevent the spread of disease was practised in many early societies. The word "quarantine" originates from the Venetian dialect form of the Italian quaranta giorni, meaning 'forty days'. This is due to the 40 day isolation of ships and people prior to entering the city of Dubrovnik in Dalmatia - Croatia (formerly known as Ragusa). This was practiced as a measure of disease prevention related to the plague (Black Death). Between 1348 and 1359 the Black Death wiped out an estimated 30% of Europe's population, as well as a significant percentage of Asia's population. The original document from 1377, which is kept in the Archives of Dubrovnik, states that before entering the city, newcomers had to spend 30 days (a trentine) in a restricted location (originally nearby islands) waiting to see whether the symptoms of plague would develop. Later on, isolation was prolonged to 40 days and was called quarantine. Other diseases lent themselves to the practice of quarantine before and after the devastation of the Plague. Those afflicted with leprosy were historically isolated from society, the attempts to check the invasion of syphilis in northern Europe about 1490, the advent of yellow fever in Spain at the beginning of the nineteenth century and the arrival of Asiatic cholera in 1831. Venice took the lead in measures to check the spread of plague, having appointed three guardians of the public health in the first years of the Black Death (1348). The next record of preventive measures comes from Reggio in Modena in 1374. The first lazaret was founded by Venice in 1403, on a small island adjoining the city; in 1467 Genova followed the example of Venice; and in 1476 the old leper hospital of Marseille was converted into a plague hospital. The great lazaret of that city, perhaps the most complete of its kind, having been founded in 1526 on the island of Pomgue. The practice at all the Mediterranean lazarets was not different from the English procedure in the Levantine and North African trade. On the approach of cholera in 1831 some new lazarets were set up at western ports, notably a very extensive establishment near Bordeaux, afterwards turned to another use.
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