Tuvan syndrome
From Star Trek : Freedom's Wiki
A degenerative, incurable neurological disease which affects mainly Vulcans, Romulans, and Rigellians. In the very early stages, the patient's eyelids are slightly displaced, facial muscles are weakened, and respiration is irregular. Loss of motor skills occurs in 10-15 years; life expectancy is 20-25 years. In less than 5% of cases, the disease can accelerate without warning.